With advances in cell culture techniques, scientists are always on a quest to find newer and more innovative formulations of media that tend to emphasize more on cell growth, viability, and output of experiments. More importantly, due to inconsistency of Fetal Bovine Serum (FBS), there is a developing demand toward those media which need less or no FBS. Advanced DMEM F12 is among the versatile and robust choices for this purpose in cell biology applications. Below, we shall discuss the future trend in the media of cell culture and how the DMEM F12 formulation fits into that. Dulbecco’s Modified Eagle’s Medium/F-12 (DMEM F-12) 1. Reduced serum use focus The most pronounced trend has been toward serum-free or low-serum media formulations. Researchers more and more remark that both the heterogeneity and the ethical concerns over Fetal Bovine Serum (FBS) give scientific justification for serum-free formulations as necessary for Advanced DMEM F12 , but again, ideally, the medium should
The antibodies in human body fabricates to defend itself are proteins; They can also be produced in labs that function just as natural ones produced by mAbs (monoclonal bodies) or mAbs (monoclonal Abs). When mAbs are generated in labs, are done by fusing the cancer cells with spleen cells of mouse, so when these cells divide and produce monoclonal antibodies. The mAb generating cells can be cryopreserved in liquid nitrogen until that mAb is needed again. Some of the mAbs are antibodies, your immune system component. They roam around in our bodies to find the antigens (foreign elements) they are supposed to kill. Science: Lab-made monoclonals boost your immunity. The term “monoclonal” describes the nature of laboratory-produced antibodies as clones. They are one antibody’s exact duplicates. The letters “mab” are frequently added to the end of the product names in their generic forms. Challenges During Producing Monoclonal Antibodies Monoclonal antibodies are produced based on hybridoma